| OBTW | | Oh, By The Way. |
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| OF | | Old Fart, someone who has been around for a while. |
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| OJ | | or OK Only Joking or Only Kidding |
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| OIC | | Oh, I see |
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| OL | | the Old Lady |
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| OLL | | Online love |
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| OM | | the Old Man |
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| OTF | | Off the floor |
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| OMG | | Oh My Gosh (although it's usually used with the Lords name in place of "gosh") |
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| OT | | Off Topic |
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| oth or OTH | | Off The Hook: Something is really popular, or hot. Very exciting. |
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| otr or OTR | | Off The Rack: Saying that something is outside the ordinary. |
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| OTE | | Over The Edge (beyond common sense or beyond good taste) |
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| OTOH | | On the other hand |
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| OTTOMH | | Off the top of my head |
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| OTW | | On The Way ... I've sent a file to you, it's "On the way" |
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